4-Hydroxybenzaldehyde

4-Hydroxybenzaldehyde

SCHEMBL2187647

O=Cc1ccc(O)cc1.[NaH]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH5A1 P51649 1/20 0.94
ABAT P80404 1/20 0.94
ALDH1A1 P00352 6/20 0.54
KDM4E B2RXH2 5/20 0.54
MAPT P10636 3/20 0.54
CYP2A6 P11509 2/20 0.50
RAB9A P51151 2/20 0.50
HSD17B10 Q99714 2/20 0.50
PTGS2 P35354 2/20 0.50
TYR P14679 4/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
F3 P13726 1/20 0.48
HSD11B1 P28845 1/20 0.48
APP P05067 1/20 0.48
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA3 P07451 2/20 0.47
CA4 P22748 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Hydroxybenzaldehyde SCHEMBL37193 0.97
4-Hydroxybenzaldehyde SCHEMBL19328157 0.97 ALDH5A1 (1.00) ALDH5A1ABATALDH1A1KDM4EMAPT
4-Hydroxybenzaldehyde SCHEMBL29952471 0.94 ALDH5A1 (0.94) ALDH5A1ABATALDH1A1KDM4EMAPT
4-Hydroxybenzaldehyde SCHEMBL28981620 0.94 ALDH5A1 (0.94) ALDH5A1ABATALDH1A1KDM4EMAPT
4-Hydroxybenzaldehyde SCHEMBL29889847 0.94 ALDH5A1 (0.94) ALDH5A1ABATALDH1A1KDM4EMAPT
4-Hydroxybenzaldehyde SCHEMBL29153364 0.94 ALDH5A1 (0.94) ALDH5A1ABATALDH1A1KDM4EMAPT
4-Hydroxybenzaldehyde SCHEMBL5161739 0.94 ALDH5A1 (0.94) ALDH5A1ABATALDH1A1KDM4EMAPT
4-Hydroxybenzaldehyde SCHEMBL28498005 0.94 ALDH5A1 (0.94) ALDH5A1ABATALDH1A1KDM4EMAPT
4-Hydroxybenzaldehyde SCHEMBL30290836 0.94 ALDH5A1 (0.94) ALDH5A1ABATALDH1A1KDM4EMAPT
4-Hydroxybenzaldehyde SCHEMBL27921866 0.94 ALDH5A1 (0.94) ALDH5A1ABATALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109111353-B Raspberry ketone reaction device and raspberry ketone continuous preparation method 诚达药业股份有限公司 2021-08-31 CN claimed
CN-111470952-A Method for preparing high-purity m-cresol by selectively oxidizing m-p-mixed cresol 厦门中坤化学有限公司 2020-07-31 CN claimed
CN-111072635-A Isoniazid-indoheptamethine cyanine coupling compound and preparation method and application thereof 沈阳药科大学 2020-04-28 CN claimed
CN-103539947-B Graft modification super high molecular weight polyacrylamide and preparation method thereof 中国石油化工股份有限公司 2016-06-08 CN claimed
CN-115231994-B Synthetic method of anisic aldehyde and method for recycling catalyst by using phase-changeable substance 山东新和成药业有限公司 2023-11-28 CN disclosed
CN-115651025-A DOPO derivative containing phosphorus amide, preparation method and application thereof 广东顺德同程新材料科技有限公司 2023-01-31 CN disclosed
CN-115231994-A Synthetic method of anisic aldehyde and method for recycling catalyst by using phase-changeable substance 山东新和成药业有限公司 2022-10-25 CN disclosed
CN-109111353-B Raspberry ketone reaction device and raspberry ketone continuous preparation method 诚达药业股份有限公司 2021-08-31 CN disclosed
CN-111072635-B Isoniazid-indoheptamethine cyanine coupling compound and preparation method and application thereof 沈阳药科大学 2021-06-11 CN disclosed
CN-106946674-B Method for synthesizing environment-friendly p-methoxybenzaldehyde 山东达冠生化科技股份有限公司 2021-04-09 CN disclosed
CN-111470952-A Method for preparing high-purity m-cresol by selectively oxidizing m-p-mixed cresol 厦门中坤化学有限公司 2020-07-31 CN disclosed
CN-111470952-A Method for preparing high-purity m-cresol by selectively oxidizing m-p-mixed cresol 厦门中坤化学有限公司 2020-07-31 CN disclosed
CN-103911104-A Lignin rock wool phenolic resin binder and its preparation method and use method HEBEI JINYUAN BUILDING MATERIALS TECHNOLOGY CO LTD 2014-07-09 CN disclosed
US-20130336997-A1 PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-12-19 US disclosed
CN-103145537-A Product separation technique for producing anisaldehyde NANJING UNIVERSITY OF TECHNOLOGY 2013-06-12 CN disclosed
EP-2341915-A1 PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS Centre National de la Recherche Scientifique (FR) 2011-07-13 EP disclosed
US-20100173871-A1 PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-07-08 US disclosed
WO-2010013086-A1 PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-02-04 WO disclosed
US-20090142316-A1 Use of Dendrimers to Stimulate Cell Growth CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2009-06-04 US disclosed
US-4205188-A CONDENSATION OF PHENOL AND FORMALDEHYDE AND REMOVAL OF EXCESS PHENOL BY SOLVENT EXTRACTION THE DOW CHEMICAL COMPANY (US) 1980-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090142316-A1 Use of Dendrimers to Stimulate Cell Growth HDGF, CD40LG, PPIP5K2 ALDH5A1 4102/4885ABAT 4036/4885ALDH1A1 4440/4885
US-20130336997-A1 PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS DUSP6, DUSP10, PTMS ALDH5A1 4598/4885ABAT 2165/4885ALDH1A1 4592/4885
US-20100173871-A1 PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS CD14, DUSP3, IRAK3 ALDH5A1 4161/4885ABAT 2382/4885ALDH1A1 4335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.