Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 2/20 | 0.48 |
| ▸ | WNT3A | P56704 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626440 | 0.78 | HDAC8 (0.50) | CTNNB1WNT3APARP1HDAC8HDAC6 | |
| SCHEMBL28534111 | 0.77 | HPGD (0.46) | CTNNB1WNT3APARP1HPGDTDP1 | |
| SCHEMBL1210113 | 0.75 | CTNNB1 (0.58) | CTNNB1WNT3APARP1HPGDTDP1 | |
| SCHEMBL31309786 | 0.75 | CTNNB1 (0.58) | CTNNB1WNT3APARP1HPGDTDP1 | |
| SCHEMBL27582425 | 0.72 | PARP1 (0.59) | PARP1HPGDTDP1HDAC8HDAC6 | |
| SCHEMBL30114847 | 0.71 | VCP (0.68) | PARP1HDAC8HDAC6SMN1; SMN2KCNK3 | |
| SCHEMBL5593353 | 0.71 | VCP (0.63) | PARP1HPGDTDP1HDAC8HDAC6 | |
| SCHEMBL28874159 | 0.71 | CTNNB1 (0.54) | CTNNB1WNT3APARP1HPGDTDP1 | |
| SCHEMBL5592874 | 0.71 | VCP (0.68) | PARP1HDAC8HDAC6SMN1; SMN2KCNK3 | |
| SCHEMBL6932732 | 0.71 | PARP1 (0.57) | PARP1HPGDTDP1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929741-A | ANTISECRETORY AGENTS, GASTRIC JUICE, ANTIULCER AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1990-05-29 | — | — | US | disclosed |