SCHEMBL27582425

SCHEMBL27582425

Cc1cccc(C(=O)[C]=O)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.59
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.52
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
HPGD P15428 2/20 0.50
KCNK3 O14649 2/20 0.50
KCNK9 Q9NPC2 2/20 0.50
KCNH2 Q12809 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
POLB P06746 2/20 0.49
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
TP53 P04637 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
KAT6A Q92794 1/20 0.45
ENPP3 O14638 1/20 0.45
ALPL P05186 1/20 0.45
XIAP P98170 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3156993 0.82 PARP1 (0.57) PARP1HDAC8HDAC6SMN1; SMN2MEN1
SCHEMBL6932732 0.82 PARP1 (0.57) PARP1HDAC8HDAC6SMN1; SMN2MEN1
SCHEMBL29503529 0.78 PARP1 (0.68) PARP1HDAC8HDAC6SMN1; SMN2MEN1
SCHEMBL3753879 0.78 PARP1 (0.68) PARP1HDAC8HDAC6SMN1; SMN2MEN1
SCHEMBL186545 0.78 PARP1 (0.68) PARP1HDAC8HDAC6SMN1; SMN2MEN1
SCHEMBL548920 0.76 PARP1 (0.65) PARP1HDAC8HDAC6SMN1; SMN2MEN1
SCHEMBL15264066 0.76 PARP1 (0.65) PARP1HDAC8HDAC6SMN1; SMN2MEN1
SCHEMBL29382709 0.76 PARP1 (0.65) PARP1HDAC8HDAC6SMN1; SMN2MEN1
SCHEMBL14406 0.76 PARP1 (0.65) PARP1HDAC8HDAC6SMN1; SMN2MEN1
SCHEMBL29639739 0.76 PARP1 (0.65) PARP1HDAC8HDAC6SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1485290-A Glass container with ultraviolet radiation protection and its making method 上海高雅玻璃有限公司 2004-03-31 CN disclosed