Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.30 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24418452 | 0.74 | TTR (0.38) | TTRALBMEN1KMT2ALOXL2 | |
| SCHEMBL28384865 | 0.74 | TTR (0.38) | TTRALBMEN1KMT2ALOXL2 | |
| SCHEMBL24129430 | 0.73 | TTR (0.58) | TTRALBMEN1KMT2AHTT | |
| SCHEMBL10429296 | 0.73 | TTR (0.37) | TTRALBLOXL2GPR35VCAM1 | |
| SCHEMBL19354876 | 0.73 | TTR (0.37) | TTRALBMEN1KMT2ALOXL2 | |
| SCHEMBL13135634 | 0.72 | CXCR2 (0.42) | TTRALBMEN1KMT2AHTT | |
| SCHEMBL17742291 | 0.70 | ALDH1A1 (0.45) | ALDH1A1KDM4E | |
| SCHEMBL28438701 | 0.70 | TTR (0.61) | TTRALBMEN1KMT2AHTT | |
| SCHEMBL2912546 | 0.70 | KMT2A (0.48) | TTRALBMEN1KMT2AHTT | |
| SCHEMBL4410714 | 0.70 | TTR (0.39) | TTRALBMEN1KMT2ALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4900859-A | Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde | HOFFMAN-LA ROCHE INC. (US) | 1990-02-13 | — | — | US | claimed |
| US-4900859-A | Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde | HOFFMAN-LA ROCHE INC. (US) | 1990-02-13 | — | — | US | disclosed |
| EP-0318826-A2 | Process for the preparation of 4-dimethylamino-3,5-dimethoxybenzaldehyde | F. HOFFMANN-LA ROCHE AG (CH) | 1989-06-07 | — | — | EP | disclosed |