Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24418452 | 0.76 | TTR (0.38) | TTRALBVCAM1LOXL2MEN1 | |
| SCHEMBL10429296 | 0.74 | TTR (0.37) | TTRALBVCAM1LOXL2GPR35 | |
| SCHEMBL19354876 | 0.74 | TTR (0.37) | TTRALBVCAM1LOXL2MEN1 | |
| SCHEMBL10429291 | 0.74 | TTR (0.52) | TTRALBVCAM1LOXL2MEN1 | |
| SCHEMBL5542222 | 0.72 | VCAM1 (0.44) | TTRALBVCAM1MEN1KMT2A | |
| SCHEMBL3679283 | 0.72 | TTR (0.54) | TTRALBVCAM1MEN1KMT2A | |
| SCHEMBL3955231 | 0.72 | TTR (0.42) | TTRALBVCAM1MEN1KMT2A | |
| SCHEMBL10337279 | 0.71 | LRRK2 (0.46) | TTRALBKDM4EALDH1A1GPR35 | |
| SCHEMBL28381748 | 0.71 | LOXL2 (0.41) | LOXL2KDM4EALDH1A1CYP2A6LMNA | |
| SCHEMBL11799632 | 0.70 | GPR35 (0.38) | ALDH1A1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | disclosed |