Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12518215 | 0.77 | KDM4E (0.40) | TTRALBGPR35VCAM1AR | |
| Hydrochloric Acid SCHEMBL2279578 | 0.76 | KDM4E (0.39) | TTRALBGPR35VCAM1AR | |
| SCHEMBL14753781 | 0.76 | VCAM1 (0.34) | TTRALBGPR35VCAM1AR | |
| SCHEMBL14606500 | 0.75 | GPR35 (0.39) | TTRALBGPR35VCAM1AR | |
| SCHEMBL24418452 | 0.74 | TTR (0.38) | TTRALBGPR35VCAM1LOXL2 | |
| SCHEMBL28384865 | 0.74 | TTR (0.38) | TTRALBGPR35VCAM1LOXL2 | |
| SCHEMBL10877523 | 0.74 | VCAM1 (0.37) | GPR35VCAM1PDE4APDE4BPDE4C | |
| SCHEMBL4342782 | 0.74 | PDE4A (0.46) | GPR35ARPDE4APDE4BPDE4C | |
| SCHEMBL7166993 | 0.73 | AR (0.42) | TTRALBGPR35VCAM1AR | |
| SCHEMBL10429291 | 0.73 | TTR (0.52) | TTRALBGPR35VCAM1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4900859-A | Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde | HOFFMAN-LA ROCHE INC. (US) | 1990-02-13 | — | — | US | claimed |
| US-4879291-A | PLANT GROWTH REGULATORS | INSTITUT FUER PFLANZENSCHUTZFORSCHUNG KLEINMACHNOW DER AKADEMIE DER LANDWIRTSCHAFTSWISSENSHAFEN DER DDR (DE) | 1989-11-07 | — | — | US | disclosed |
| US-4737498-A | N-alkyl-2,6-dimethylmorpholinocarboxamide salts, compositions and their use as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 1988-04-12 | — | — | US | disclosed |