SCHEMBL10429481

SCHEMBL10429481

CN(C)S(=O)(=O)c1cccc(O)c1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HTT P42858 1/20 0.43
CDK2 P24941 1/20 0.43
POLB P06746 2/20 0.42
G6PD P11413 1/20 0.40
CASP7 P55210 1/20 0.40
CASP6 P55212 1/20 0.40
MCL1 Q07820 1/20 0.40
CA2 P00918 2/20 0.39
STAT3 P40763 1/20 0.39
ALOX5AP P20292 2/20 0.38
FEN1 P39748 2/20 0.38
AURKA O14965 1/20 0.37
AURKB Q96GD4 1/20 0.37
NPC1 O15118 1/20 0.37
TNF P01375 1/20 0.37
RAB9A P51151 1/20 0.37
NOD1 Q9Y239 1/20 0.37
CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10877565 0.81 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2HTTPOLBCA2
SCHEMBL26417358 0.80 HTR2A (0.39) ALDH1A1CDK2G6PDCASP7CASP6
SCHEMBL14894969 0.80 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2HTTCDK2POLB
SCHEMBL9359459 0.79 CDK2 (0.47) ALDH1A1CDK2POLBG6PDCASP7
SCHEMBL565103 0.78 CDK2 (0.50) ALDH1A1CDK2POLBG6PDCASP7
SCHEMBL635927 0.78 CDK2 (0.61) ALDH1A1CDK2G6PDCASP7CASP6
SCHEMBL29545862 0.78 CDK2 (0.50) ALDH1A1CDK2POLBG6PDCASP7
SCHEMBL9351766 0.78 CDK2 (0.61) ALDH1A1SMN1; SMN2HTTCDK2POLB
SCHEMBL12086969 0.78 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2HTTPOLBMCL1
SCHEMBL24478481 0.77 MCL1 (0.50) ALDH1A1SMN1; SMN2HTTPOLBG6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4935500-A Blue color SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-06-19 US disclosed
EP-0099721-B1 REACTIVE METAL FORMAZAN BLUE DYE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-10-29 EP disclosed
EP-0099721-A1 Reactive metal formazan blue dye SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-02-01 EP disclosed