SCHEMBL9359459

SCHEMBL9359459

CS(=O)(=O)c1cccc(O)c1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 1/20 0.47
G6PD P11413 1/20 0.44
CASP7 P55210 1/20 0.44
CASP6 P55212 1/20 0.44
STAT3 P40763 1/20 0.42
AURKA O14965 1/20 0.40
AURKB Q96GD4 1/20 0.40
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39
CA12 O43570 2/20 0.39
CYP2C9 P11712 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
NR4A1 P22736 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL565103 0.83 CDK2 (0.50) CDK2G6PDCASP7CASP6STAT3
SCHEMBL635927 0.83 CDK2 (0.61) CDK2G6PDCASP7CASP6STAT3
SCHEMBL29545862 0.83 CDK2 (0.50) CDK2G6PDCASP7CASP6STAT3
SCHEMBL3030721 0.81 AURKA (0.53) CDK2G6PDCASP7CASP6STAT3
SCHEMBL6622710 0.81 CA2 (0.50) CDK2STAT3CA1CA2CA9
SCHEMBL4458549 0.80 CDK2 (0.44) CDK2G6PDCASP7CASP6STAT3
SCHEMBL10429481 0.79 ALDH1A1 (0.45) CDK2G6PDCASP7CASP6STAT3
SCHEMBL1110597 0.78 GAA (0.48) G6PDCA1CA2CA9CA12
SCHEMBL6828498 0.78 CDK2 (0.48) CDK2STAT3CA1CA2CA6
SCHEMBL71032 0.78 BCAT2 (0.44) CDK2STAT3CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0385890-B1 Pocess for the preparation of stilbene derivatives EASTMAN CHEM CO (US) 1994-10-19 EP claimed
EP-0472525-A1 PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES EASTMAN KODAK COMPANY (US) 1992-03-04 EP claimed
WO-1990010001-A1 PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES EASTMAN KODAK COMPANY (US) 1990-09-07 WO claimed
EP-0385890-A1 Pocess for the preparation of stilbene derivatives EASTMAN CHEMICAL COMPANY (US) 1990-09-05 EP claimed
US-4921964-A Process for the preparation of stilbene derivatives EASTMAN KODAK COMPANY (US) 1990-05-01 US claimed
CN-102753018-A Preparation of benzofurans and their use as synthetic intermediates MAPI PHARMA HOLDINGS CYPRUS LTD 2012-10-24 CN disclosed
EP-0385890-B1 Pocess for the preparation of stilbene derivatives EASTMAN CHEM CO (US) 1994-10-19 EP disclosed
EP-0472525-A1 PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES EASTMAN KODAK COMPANY (US) 1992-03-04 EP disclosed
WO-1990010001-A1 PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES EASTMAN KODAK COMPANY (US) 1990-09-07 WO disclosed
EP-0385890-A1 Pocess for the preparation of stilbene derivatives EASTMAN CHEMICAL COMPANY (US) 1990-09-05 EP disclosed
US-4921964-A Process for the preparation of stilbene derivatives EASTMAN KODAK COMPANY (US) 1990-05-01 US disclosed