SCHEMBL635927

SCHEMBL635927

Nc1c(O)cccc1S(N)(=O)=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 1/20 0.61
STAT3 P40763 1/20 0.53
CA2 P00918 9/20 0.52
CA1 P00915 8/20 0.52
CA9 Q16790 7/20 0.52
CA6 P23280 3/20 0.52
CA12 O43570 3/20 0.52
CA5A P35218 3/20 0.52
CA4 P22748 2/20 0.52
CA7 P43166 2/20 0.52
CA5B Q9Y2D0 2/20 0.52
CYP2C9 P11712 1/20 0.52
CA14 Q9ULX7 1/20 0.52
G6PD P11413 1/20 0.47
CASP7 P55210 1/20 0.47
CASP6 P55212 1/20 0.47
LDHA P00338 1/20 0.45
AURKA O14965 1/20 0.42
AURKB Q96GD4 1/20 0.42
APEX1 P27695 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL565103 0.86 CDK2 (0.50) CDK2STAT3CA2CA1CA9
SCHEMBL29545862 0.86 CDK2 (0.50) CDK2STAT3CA2CA1CA9
SCHEMBL3030721 0.84 AURKA (0.53) CDK2STAT3CA2CA1CA9
SCHEMBL9359459 0.83 CDK2 (0.47) CDK2STAT3CA2CA1CA9
SCHEMBL4458549 0.79 CDK2 (0.44) CDK2STAT3CA2CA1CA9
SCHEMBL5518503 0.79 CDK2 (0.63) CDK2STAT3CA2CA1CA9
SCHEMBL7761041 0.79 CA2 (0.67) CDK2STAT3CA2CA1CA9
SCHEMBL184251 0.78 CDK2 (0.61) CDK2STAT3CA2CA1CA9
SCHEMBL29965023 0.78 CDK2 (0.61) CDK2STAT3CA2CA1CA9
SCHEMBL564663 0.78 HTR6 (0.58) CDK2CA2CA1CA9CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5376151-A Using iron complexes of azo dyes in place of chromium-based ones NORTH CAROLINA STATE UNIVERSITY (US) 1994-12-27 US claimed
CN-116721709-A Method for detecting antibacterial activity of compound mixed sample 浙江省水利河口研究院(浙江省海洋规划设计研究院) 2023-09-08 CN disclosed
EP-2302000-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2016-11-16 EP disclosed
US-9051501-B2 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2015-06-09 US disclosed
EP-2100923-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2013-03-13 EP disclosed
EP-2088173-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2012-02-22 EP disclosed
US-8008386-B2 Curable composition KANEKA CORPORATION (JP) 2011-08-30 US disclosed
EP-2302000-A1 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2011-03-30 EP disclosed
US-20100063215-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2010-03-11 US disclosed
US-20100041810-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORPORATION (JP) 2010-02-18 US disclosed
WO-2010003970-A2 PHENOXAZINE DYES Wetlands Incubator sprl (BE) 2010-01-14 WO disclosed
WO-2010003970-A2 PHENOXAZINE DYES Wetlands Incubator sprl (BE) 2010-01-14 WO disclosed
US-20100000032-A1 PHENOXAZINE DYES Wetlands Incubator sprl (BE) 2010-01-07 US disclosed
US-20100000032-A1 PHENOXAZINE DYES Wetlands Incubator sprl (BE) 2010-01-07 US disclosed
US-20100000032-A1 PHENOXAZINE DYES Wetlands Incubator sprl (BE) 2010-01-07 US disclosed
EP-2100923-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2009-09-16 EP disclosed
EP-2088173-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION Kaneka Corporation (JP) 2009-08-12 EP disclosed
EP-0777703-A2 DICYCLIC METAL COMPLEX FORMAZAN DERIVATIVES, PROCESS FOR PRODUCING THE SAME, COMPOSITION CONTAINING THE SAME AND DYEING PROCESS EMPLOYING THE SAME Kyungin Synthetic Corporation (KR) 1997-06-11 EP disclosed
WO-1996033240-A2 DICYCLIC METAL COMPLEX FORMAZAN DERIVATIVES, PROCESS FOR PRODUCING THE SAME, COMPOSITION CONTAINING THE SAME AND DYEING PROCESS EMPLOYING THE SAME KYUNG-IN SYNTHETIC CORPORATION (KR) 1996-10-24 WO disclosed
US-5376151-A Using iron complexes of azo dyes in place of chromium-based ones NORTH CAROLINA STATE UNIVERSITY (US) 1994-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100000032-A1 PHENOXAZINE DYES H1-5, IK, PPOX CDK2 307/4885STAT3 2899/4885CA2 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.