Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | APAF1 | O14727 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4360395 | 0.82 | SMN1; SMN2 (0.44) | LMNAAPAF1POLBSMN1; SMN2KDM4E | |
| SCHEMBL8145390 | 0.79 | CHRM1 (0.36) | LMNAAPAF1POLBKDM4EBAZ2B | |
| SCHEMBL25183809 | 0.79 | LMNA (0.41) | LMNAAPAF1POLBSMN1; SMN2KDM4E | |
| SCHEMBL23240257 | 0.78 | SMN1; SMN2 (0.39) | LMNAAPAF1POLBSMN1; SMN2KDM4E | |
| SCHEMBL678753 | 0.77 | SMN1; SMN2 (0.37) | LMNAAPAF1POLBSMN1; SMN2KDM4E | |
| SCHEMBL27718196 | 0.75 | HSD17B10 (0.43) | LMNAAPAF1POLBSMN1; SMN2KDM4E | |
| SCHEMBL24248353 | 0.72 | PDE2A (0.36) | LMNAAPAF1POLBSMN1; SMN2KDM4E | |
| SCHEMBL15686686 | 0.71 | MEN1 (0.42) | LMNASMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL31057128 | 0.71 | MAPT (0.49) | KDM4EALDH1A1 | |
| SCHEMBL286931 | 0.69 | KDM4E (0.58) | LMNAAPAF1POLBSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2292263-A | — | — | None | — | — | JP | disclosed |
| JP-H02292263-A | PRODUCTION OF 1-METHYL-3-ALKYL-5-PYRAZOLE CARBOXYLATE | MITSUBISHI KASEI CORP | 1990-12-03 | — | — | JP | disclosed |