Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429623 | 0.79 | LMNA (0.45) | POLBLMNAAPAF1ALDH1A1KDM4E | |
| SCHEMBL12248406 | 0.78 | RECQL (0.33) | RECQL | |
| 3-Chloro-1-Methyl-1H-Pyrazole-5-Carboxylic Acid SCHEMBL1915166 | 0.71 | GRN (0.56) | ALDH1A1KDM4EGRNSORT1MEN1 | |
| SCHEMBL31057128 | 0.69 | MAPT (0.49) | ALDH1A1KDM4E | |
| SCHEMBL12983862 | 0.68 | SMN1; SMN2 (0.47) | POLBLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2216049 | 0.68 | HCAR3 (0.34) | PTGS1POLBLMNAAPAF1AKR1C3 | |
| SCHEMBL3058674 | 0.67 | KDM4E (0.39) | LMNAALDH1A1KDM4EGRNSORT1 | |
| SCHEMBL11631341 | 0.67 | ALDH1A1 (0.43) | POLBLMNAAPAF1ALDH1A1KDM4E | |
| SCHEMBL31348077 | 0.67 | SMN1; SMN2 (0.42) | POLBLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL1305126 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020447-A1 | PYRAZOLE COMPOUNDS AND PLANT DISEASE CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |