Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429772 | 0.76 | P2RX7 (0.33) | — | |
| SCHEMBL23532338 | 0.76 | ELANE (0.36) | ELANETDP1ALDH1A1HPGDKDM4E | |
| SCHEMBL23532369 | 0.75 | ELANE (0.38) | ELANETDP1ALDH1A1HPGDKDM4E | |
| SCHEMBL14670357 | 0.74 | HDAC4 (0.33) | ALDH1A1 | |
| SCHEMBL4999758 | 0.74 | PTGS2 (0.31) | ELANECYP1A2GRM5TDP1MEN1 | |
| SCHEMBL4999690 | 0.74 | CYP1A2 (0.31) | ELANECYP1A2GRM5TDP1MEN1 | |
| SCHEMBL273322 | 0.71 | NR1H2 (0.59) | NR1H2NR1H3ESR1ESR2TDP1 | |
| SCHEMBL4989981 | 0.70 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL5005188 | 0.70 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL4245640 | 0.69 | HDAC4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6092975-A | — | — | None | — | — | JP | disclosed |
| JP-H0692975-A | NEW SILANOL | TONEN CHEM CORP | 1994-04-05 | — | — | JP | disclosed |