Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27188704 | 0.91 | LRRK2 (0.50) | FFAR4FFAR1NR1H4ALDH1A1LMNA | |
| SCHEMBL7911106 | 0.88 | ALDH1A1 (0.55) | NR1H4ALDH1A1LMNAL3MBTL1NPC1 | |
| SCHEMBL69725 | 0.88 | SGMS2 (0.52) | NR1H4ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL30535266 | 0.88 | SGMS2 (0.52) | NR1H4ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL28790534 | 0.83 | FFAR4 (0.54) | FFAR4FFAR1ALDH1A1LMNAMAPT | |
| SCHEMBL2944769 | 0.82 | ALDH1A1 (0.47) | FFAR4NR1H4ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL3956579 | 0.82 | ALDH1A1 (0.47) | FFAR4NR1H4ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL26666325 | 0.81 | LRRK2 (0.52) | FFAR4NR1H4ALDH1A1LMNAMAPT | |
| SCHEMBL19766826 | 0.81 | MCL1 (0.47) | FFAR4NR1H4ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL12939113 | 0.81 | NR1H4 (0.46) | FFAR4NR1H4ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105462-A1 | MODULATORS OF DOPAMINE NEUROTRANSMISSION | NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE (DK) | 2011-05-05 | — | — | US | disclosed |
| EP-2271635-A1 | MODULATORS OF DOPAMINE NEUROTRANSMISSION | NSAB, Filial af NeuroSearch Sweden AB, Sverige (DK) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009133109-A1 | MODULATORS OF DOPAMINE NEUROTRANSMISSION | NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE (DK) | 2009-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105462-A1 | MODULATORS OF DOPAMINE NEUROTRANSMISSION | DBH, SLC18A2, SLC6A3 | FFAR4 2284/4885FFAR1 2523/4885NR1H4 1068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.