SCHEMBL26666325

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27188479	0.88	PTGER1 (0.52)	LRRK2PTGER1MRGPRX4
	SCHEMBL27188704	0.88	LRRK2 (0.50)	LRRK2NR1H4ALDH1A1MRGPRX4FFAR4
	SCHEMBL6820830	0.88	MRGPRX4 (0.46)	LRRK2PTGER1PTGER4PTGER3PTGER2
	SCHEMBL69725	0.88	SGMS2 (0.52)	PTGER1NR1H4ALDH1A1NPC1MAPT
	SCHEMBL30535266	0.88	SGMS2 (0.52)	PTGER1NR1H4ALDH1A1NPC1MAPT
	SCHEMBL38657361	0.85	LRRK2 (0.53)	LRRK2PTGER1PTGER4PTGER3PTGER2
	SCHEMBL2944769	0.84	ALDH1A1 (0.47)	LRRK2NR1H4ALDH1A1FFAR4SMN1; SMN2
	SCHEMBL3956579	0.84	ALDH1A1 (0.47)	NR1H4ALDH1A1MRGPRX4FFAR4SMN1; SMN2
	SCHEMBL7911106	0.83	ALDH1A1 (0.55)	NR1H4ALDH1A1SMN1; SMN2NPC1RAB9A
	SCHEMBL12939113	0.83	NR1H4 (0.46)	LRRK2NR1H4ALDH1A1FFAR4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.