Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355295 | 0.92 | REN (0.44) | RENACE | |
| SCHEMBL7355301 | 0.92 | REN (0.44) | RENACE | |
| SCHEMBL10447999 | 0.92 | REN (0.42) | RENCTSD | |
| SCHEMBL10447998 | 0.92 | REN (0.42) | RENCTSD | |
| SCHEMBL8252710 | 0.81 | REN (0.38) | RENACECTSD | |
| SCHEMBL11010625 | 0.80 | REN (0.66) | REN | |
| SCHEMBL11013919 | 0.80 | REN (0.66) | REN | |
| SCHEMBL29641501 | 0.78 | CTSD (0.44) | RENCTSD | |
| SCHEMBL16359592 | 0.77 | ACE (0.39) | ACE | |
| SCHEMBL30684922 | 0.77 | CTSD (0.44) | RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400290-A1 | 5-Amino-4-hydroxyvalerianic acid derivatives useful as intermediates in the preparation of renin inhibitors | CIBA-GEIGY AG (CH) | 1990-12-05 | — | — | EP | claimed |
| EP-0129690-A2 | Process for the preparation of 4,4',7,7'-tetrachlorothioindigo pigments | BAYER AG (DE) | 1985-01-02 | — | — | EP | disclosed |