Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.53 |
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339009 | 0.87 | CYP1B1 (0.61) | LCKKDM4EALDH1A1CYP3A4MAPK1 | |
| SCHEMBL10432575 | 0.86 | CYP1B1 (0.62) | KDM4EALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL10432903 | 0.85 | ABCB1 (0.66) | KDM4EALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL10432589 | 0.82 | CYP3A4 (0.65) | LCKKDM4EALDH1A1CYP3A4MAPK1 | |
| SCHEMBL10432914 | 0.82 | TERT (0.54) | KDM4EALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL10432915 | 0.79 | MAPT (0.53) | KDM4EALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL10432576 | 0.79 | ALDH1A1 (0.64) | KDM4EALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL4649423 | 0.78 | KDM4E (0.77) | KDM4EALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL10433067 | 0.78 | TERT (0.50) | KDM4EALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL31376250 | 0.75 | ALDH1A1 (0.81) | KDM4EALDH1A1CYP3A4MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0374789-A1 | 5- Aminoflavone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-06-27 | — | — | EP | disclosed |