Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 2/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.56 |
| ▸ | TUBB | P07437 | 1/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10432914 | 0.91 | TERT (0.54) | CYP1B1CYP1A1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL10339009 | 0.88 | CYP1B1 (0.61) | CYP1B1CYP1A1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL10432903 | 0.88 | ABCB1 (0.66) | CYP1B1CYP1A1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL10432787 | 0.86 | LCK (0.56) | CYP1B1CYP1A1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL10433067 | 0.86 | TERT (0.50) | CYP1B1CYP1A1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL10432915 | 0.79 | MAPT (0.53) | CYP1B1CYP1A1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL10432576 | 0.79 | ALDH1A1 (0.64) | CYP1B1CYP1A1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL10432584 | 0.78 | ESR1 (0.68) | CYP1B1CYP1A1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL987020 | 0.77 | ALDH1A1 (0.73) | CYP1B1CYP1A1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL31238014 | 0.77 | ALDH1A1 (0.73) | CYP1B1CYP1A1CYP1A2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0374789-A1 | 5- Aminoflavone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-06-27 | — | — | EP | disclosed |