Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 8/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.62 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10432915 | 0.92 | MAPT (0.53) | ALDH1A1CYP3A4HPGDMAPTKDM4E | |
| SCHEMBL10433068 | 0.87 | MAPT (0.48) | ALDH1A1CYP3A4HPGDMAPTKDM4E | |
| SCHEMBL10339009 | 0.85 | CYP1B1 (0.61) | ALDH1A1CYP3A4HPGDMAPTKDM4E | |
| SCHEMBL10432585 | 0.83 | ALDH1A1 (0.63) | ALDH1A1CYP3A4HPGDMAPTKDM4E | |
| SCHEMBL10432914 | 0.80 | TERT (0.54) | ALDH1A1CYP3A4HPGDMAPTKDM4E | |
| SCHEMBL10432903 | 0.80 | ABCB1 (0.66) | ALDH1A1CYP3A4HPGDMAPTKDM4E | |
| SCHEMBL10432575 | 0.79 | CYP1B1 (0.62) | ALDH1A1CYP3A4HPGDMAPTKDM4E | |
| SCHEMBL10432787 | 0.79 | LCK (0.56) | ALDH1A1CYP3A4HPGDMAPTKDM4E | |
| 8,2'-Dimethoxyflavone SCHEMBL516353 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HPGDMAPTKDM4E | |
| SCHEMBL1676007 | 0.76 | ALDH1A1 (0.74) | ALDH1A1CYP3A4HPGDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0374789-A1 | 5- Aminoflavone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-06-27 | — | — | EP | disclosed |