Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434157 | 1.00 | LMNA (0.30) | LMNA | |
| SCHEMBL10433858 | 1.00 | LMNA (0.30) | LMNA | |
| SCHEMBL10434209 | 0.86 | MET (0.30) | — | |
| SCHEMBL10434211 | 0.86 | MET (0.30) | — | |
| SCHEMBL8979377 | 0.82 | PTGS2 (0.36) | LMNA | |
| SCHEMBL8979406 | 0.82 | PTGS2 (0.36) | LMNA | |
| SCHEMBL10433856 | 0.79 | VCAM1 (0.35) | — | |
| SCHEMBL10433857 | 0.79 | VCAM1 (0.35) | — | |
| SCHEMBL10434005 | 0.79 | VCAM1 (0.35) | — | |
| SCHEMBL29137878 | 0.78 | CDK1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368410-A2 | Optically active benzoxazines and bezothiazines and a process for their stereospecific preparation | GIST-BROCADES N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |