Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.53 |
| ▸ | CTSD | P07339 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10433839 | 0.85 | CTSD (0.42) | RENCTSD | |
| SCHEMBL10433908 | 0.77 | REN (0.41) | REN | |
| SCHEMBL10664132 | 0.75 | REN (0.62) | REN | |
| SCHEMBL10664115 | 0.75 | REN (0.62) | REN | |
| SCHEMBL10662212 | 0.75 | REN (0.60) | RENCTSD | |
| SCHEMBL10659887 | 0.75 | REN (0.60) | RENCTSD | |
| SCHEMBL29612424 | 0.75 | REN (0.59) | RENCTSD | |
| SCHEMBL9716892 | 0.74 | REN (0.65) | REN | |
| SCHEMBL10632103 | 0.73 | CTSD (0.48) | RENCTSD | |
| SCHEMBL10630585 | 0.73 | REN (0.63) | RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369141-A1 | Aspartic protease inhibitors for the treatment of diseases caused by retroviruses | MERCK PATENT GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |