SCHEMBL10434603

SCHEMBL10434603

C[S+](C)c1ccccc1OC(=O)[O-]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.36
ATM Q13315 1/20 0.36
HSD17B10 Q99714 5/20 0.35
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 2/20 0.35
PTGS1 P23219 2/20 0.35
ESR1 P03372 1/20 0.35
ITGB3 P05106 1/20 0.35
ITGA2B P08514 1/20 0.35
HMGB1 P09429 1/20 0.35
TSHR P16473 1/20 0.35
GGT1 P19440 1/20 0.35
PTGS2 P35354 1/20 0.35
BLM P54132 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
ELANE P08246 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9853827 0.89 KDM4E (0.31) TDP1ATMHSD17B10KDM4EALDH1A1
SCHEMBL10434602 0.84 HSD17B10 (0.43) TDP1ATMHSD17B10KDM4EALDH1A1
SCHEMBL9543319 0.77 THRB (0.49) TDP1ATMHSD17B10KDM4EALDH1A1
SCHEMBL7901803 0.75 ELANE (0.41) TDP1ATMHSD17B10KDM4EALDH1A1
SCHEMBL10594922 0.75 PTGS2 (0.42) TDP1HSD17B10KDM4EALDH1A1HPGD
SCHEMBL9853828 0.75 BCHE (0.36) TDP1ATMHSD17B10KDM4EALDH1A1
SCHEMBL11077954 0.73 PTGS2 (0.52) TDP1HSD17B10KDM4EALDH1A1HPGD
SCHEMBL4368552 0.72 ELANE (0.38) TDP1ATMHSD17B10KDM4EALDH1A1
SCHEMBL5828193 0.70 CA1 (0.57) TDP1HSD17B10KDM4EALDH1A1HPGD
Trifluoromethanesulfonic Acid SCHEMBL8429688 0.69 ELANE (0.35) TDP1ATMHSD17B10KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0401696-A2 Process for production of sulfonium compounds and novel methylthiophenyl derivatives MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1990-12-12 EP disclosed