Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841280 | 0.81 | THRB (0.56) | THRBTHRAKDM4EHPGDHSD17B10 | |
| SCHEMBL29413361 | 0.81 | THRB (0.56) | THRBTHRAKDM4EHPGDHSD17B10 | |
| SCHEMBL501365 | 0.80 | THRB (0.43) | THRBTHRAKDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL4411919 | 0.80 | TYMS (0.45) | THRBTHRAHSD17B10TYMSMAPK1 | |
| SCHEMBL10434602 | 0.80 | HSD17B10 (0.43) | KDM4EHPGDHSD17B10MAPTTDP1 | |
| SCHEMBL30438185 | 0.79 | TDP1 (0.58) | THRBTHRAKDM4EHPGDHSD17B10 | |
| SCHEMBL34006 | 0.79 | TDP1 (0.58) | THRBTHRAKDM4EHPGDHSD17B10 | |
| SCHEMBL29999157 | 0.77 | THRA (0.53) | THRBTHRAKDM4EMAPTTDP1 | |
| SCHEMBL5604717 | 0.77 | THRB (0.53) | THRBTHRAKDM4EHPGDHSD17B10 | |
| SCHEMBL2235806 | 0.77 | THRA (0.53) | THRBTHRAKDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5043714-A | — | — | None | — | — | JP | disclosed |
| JP-H0543714-A | FILM | SANSHIN CHEM IND CO LTD | 1993-02-23 | — | — | JP | disclosed |