Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434603 | 0.89 | TDP1 (0.36) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL10594922 | 0.79 | PTGS2 (0.42) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL9853828 | 0.79 | BCHE (0.36) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL4368552 | 0.75 | ELANE (0.38) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL10434602 | 0.75 | HSD17B10 (0.43) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL9442120 | 0.72 | PKM (0.39) | HSD17B10ALDH1A1LMNAHTTCA12 | |
| SCHEMBL9543319 | 0.68 | THRB (0.49) | KDM4EHPGDHSD17B10ALDH1A1ATM | |
| SCHEMBL8634038 | 0.67 | MYC (0.36) | HSD17B10ALDH1A1LMNACA1CA2 | |
| Trifluoromethanesulfonic Acid SCHEMBL8429688 | 0.67 | ELANE (0.35) | KDM4EHPGDHSD17B10ATMTDP1 | |
| Methacrylic Acid SCHEMBL4870456 | 0.67 | ELANE (0.32) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406567-A2 | Process for the production of sulfonium compounds and novel methylthiophenol derivatives | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1991-01-09 | — | — | EP | disclosed |
| EP-0401696-A2 | Process for production of sulfonium compounds and novel methylthiophenyl derivatives | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-12-12 | — | — | EP | disclosed |
| EP-0346756-A1 | Process for production of sulfonium compounds | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-12-20 | — | — | EP | disclosed |