SCHEMBL10434833

SCHEMBL10434833

COCCC(CO)c1cccc(OCc2ccc3ccccc3c2)c1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 12/20 0.53
F2 P00734 1/20 0.41
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10434841 0.91 ALOX5 (0.53) ALOX5
SCHEMBL9577510 0.79 ALOX5 (0.60) ALOX5F2
SCHEMBL9577523 0.77 ALOX5 (0.58) ALOX5F2
SCHEMBL10431671 0.75 ALOX5 (0.53) ALOX5FNTAFNTB
SCHEMBL9148495 0.75 ALOX5 (0.53) ALOX5F2FNTAFNTB
SCHEMBL10656521 0.74 ALOX5 (0.69) ALOX5
SCHEMBL10434831 0.73 ALOX5 (0.54) ALOX5F2
SCHEMBL10434840 0.72 ALOX5 (0.56) ALOX5
SCHEMBL9151512 0.71 ALOX5 (0.52) ALOX5FNTAFNTB
SCHEMBL9150430 0.71 ALOX5 (0.55) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0375368-A2 Alcohol and ether derivatives ZENECA LIMITED (GB) 1990-06-27 EP disclosed