Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 13/20 | 0.53 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434833 | 0.91 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL10445571 | 0.79 | MAPK1 (0.39) | — | |
| SCHEMBL10434840 | 0.74 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9577523 | 0.73 | ALOX5 (0.58) | ALOX5TLR4TLR2 | |
| SCHEMBL10656521 | 0.73 | ALOX5 (0.69) | ALOX5 | |
| SCHEMBL9577510 | 0.73 | ALOX5 (0.60) | ALOX5TLR4TLR2 | |
| SCHEMBL10434831 | 0.72 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL9148495 | 0.72 | ALOX5 (0.53) | ALOX5TLR4TLR2 | |
| SCHEMBL9688759 | 0.72 | ALOX5 (0.51) | ALOX5TLR4TLR2 | |
| SCHEMBL19210360 | 0.71 | TACR1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375368-A2 | Alcohol and ether derivatives | ZENECA LIMITED (GB) | 1990-06-27 | — | — | EP | disclosed |