Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434840 | 0.88 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9577510 | 0.77 | ALOX5 (0.60) | ALOX5MAPK1TP53CYP1A2CYP3A4 | |
| SCHEMBL10656521 | 0.77 | ALOX5 (0.69) | ALOX5MAPK1TP53CYP1A2CYP3A4 | |
| SCHEMBL9577523 | 0.75 | ALOX5 (0.58) | ALOX5MAPK1TP53CYP1A2CYP3A4 | |
| SCHEMBL9577539 | 0.74 | ALOX5 (0.54) | ALOX5MAPK1TP53CYP1A2CYP3A4 | |
| SCHEMBL9688759 | 0.73 | ALOX5 (0.51) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL9598079 | 0.73 | ALOX5 (0.56) | ALOX5MAPK1TP53CYP1A2CYP3A4 | |
| SCHEMBL10434833 | 0.73 | ALOX5 (0.53) | ALOX5F2 | |
| SCHEMBL9150430 | 0.72 | ALOX5 (0.55) | ALOX5MAPK1TP53CYP1A2CYP3A4 | |
| SCHEMBL10434841 | 0.72 | ALOX5 (0.53) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375368-A2 | Alcohol and ether derivatives | ZENECA LIMITED (GB) | 1990-06-27 | — | — | EP | disclosed |