Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.97 |
| ▸ | DHODH | Q02127 | 5/20 | 0.97 |
| ▸ | MEN1 | O00255 | 4/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.97 |
| ▸ | PKM | P14618 | 2/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.97 |
| ▸ | GMNN | O75496 | 1/20 | 0.97 |
| ▸ | TTR | P02766 | 1/20 | 0.97 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.97 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.97 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.97 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.97 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.97 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.97 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.97 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.97 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.97 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.97 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niflumic Acid SCHEMBL29373503 | 0.99 | DHODH (1.00) | LMNADHODHMEN1KMT2APKM | |
| Niflumic Acid SCHEMBL24706 | 0.99 | DHODH (1.00) | LMNADHODHMEN1KMT2APKM | |
| Niflumic Acid SCHEMBL29364001 | 0.99 | DHODH (1.00) | LMNADHODHMEN1KMT2APKM | |
| Niflumic Acid SCHEMBL4886924 | 0.99 | DHODH (1.00) | LMNADHODHMEN1KMT2APKM | |
| Niflumic Acid SCHEMBL8925125 | 0.97 | DHODH (0.97) | LMNADHODHMEN1KMT2APKM | |
| Niflumic Acid SCHEMBL5251418 | 0.91 | LMNA (0.84) | LMNADHODHMEN1KMT2APKM | |
| Niflumic Acid SCHEMBL5305825 | 0.89 | LMNA (0.81) | LMNADHODHMEN1KMT2APKM | |
| SCHEMBL12608890 | 0.87 | LMNA (0.79) | LMNADHODHMEN1KMT2APKM | |
| SCHEMBL4204237 | 0.87 | LMNA (0.79) | LMNADHODHMEN1KMT2APKM | |
| SCHEMBL22492824 | 0.86 | LMNA (0.78) | LMNADHODHMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115813902-A | Use of substituted hexitols for the treatment of malignant tumors | 德玛公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115778934-A | Use of substituted hexitols for the treatment of malignant tumors | 德玛公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-110711188-A | Use of substituted hexitols for the treatment of malignant tumors | 德玛公司 | 2020-01-21 | — | — | CN | disclosed |
| CN-1763012-A | Sodium niflumic acid production process | GU YUMEI (CN) | 2006-04-26 | — | — | CN | disclosed |
| EP-0349902-A2 | Processes for the preparation of morniflumate and analogous compounds | CHIESI FARMACEUTICI S.p.A. (IT) | 1990-01-10 | — | — | EP | disclosed |