Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 1.00 |
| ▸ | TTR | P02766 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | UGT1A1 | P22309 | 1/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | TEAD4 | Q15561 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niflumic Acid SCHEMBL29364001 | 1.00 | DHODH (1.00) | DHODHLMNAMEN1KMT2APKM | |
| Niflumic Acid SCHEMBL29373503 | 1.00 | DHODH (1.00) | DHODHLMNAMEN1KMT2APKM | |
| Niflumic Acid SCHEMBL24706 | 1.00 | DHODH (1.00) | DHODHLMNAMEN1KMT2APKM | |
| Niflumic Acid SCHEMBL8925125 | 0.99 | DHODH (0.97) | DHODHLMNAMEN1KMT2APKM | |
| Niflumic Acid SCHEMBL10435526 | 0.99 | LMNA (0.97) | DHODHLMNAMEN1KMT2APKM | |
| Niflumic Acid SCHEMBL5251418 | 0.92 | LMNA (0.84) | DHODHLMNAMEN1KMT2APKM | |
| Niflumic Acid SCHEMBL5305825 | 0.90 | LMNA (0.81) | DHODHLMNAMEN1KMT2APKM | |
| SCHEMBL12608890 | 0.88 | LMNA (0.79) | DHODHLMNAMEN1KMT2APKM | |
| SCHEMBL4204237 | 0.88 | LMNA (0.79) | DHODHLMNAMEN1KMT2APKM | |
| SCHEMBL22492824 | 0.88 | LMNA (0.78) | DHODHLMNAMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039522-A1 | Composition Containing a Complex Comprising a Metal Ion and a Carboxylate Ligand Having Anti-Inflammatory Activity | MEDICAL THERAPIES LIMITED (AU) | 2008-02-14 | — | — | US | disclosed |
| EP-1734945-A4 | A COMPOSITION CONTAINING A COMPLEX COMPRISING A METAL ION AND A CARBOXYLATE LIGAND HAVING ANTI-INFLAMMATORY ACTIVITY | MEDICAL THERAPIES LTD (AU) | 2007-10-03 | — | — | EP | disclosed |
| EP-1734945-A1 | A COMPOSITION CONTAINING A COMPLEX COMPRISING A METAL ION AND A CARBOXYLATE LIGAND HAVING ANTI-INFLAMMATORY ACTIVITY | THE UNIVERSITY OF SYDNEY (AU) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005094809-A1 | A COMPOSITION CONTAINING A COMPLEX COMPRISING A METAL ION AND A CARBOXYLATE LIGAND HAVING ANTI-INFLAMMATORY ACTIVITY | MEDICAL THERAPIES LIMITED (AU) | 2005-10-13 | — | — | WO | disclosed |
| US-4292319-A | MIXTURE WITH AN ANTIULCER AGENT | BOEHRINGER INGELHEIM GMBH (DE) | 1981-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039522-A1 | Composition Containing a Complex Comprising a Metal Ion and a Carboxylate Ligand Having Anti-Inflammatory Activity | MIF, TNF, LITAF | DHODH 1474/4885LMNA 4437/4885MEN1 2162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.