Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633143 | 0.79 | ALDH1A1 (0.34) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL14679607 | 0.76 | ALDH1A1 (0.39) | CYP19A1KDM4ELMNAALDH1A1GAA | |
| SCHEMBL25151746 | 0.75 | CHEK1 (0.32) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL5633206 | 0.73 | SMPD3 (0.35) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL10520551 | 0.72 | GABRA1 (0.41) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL23107051 | 0.72 | SUV39H2 (0.33) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL4003688 | 0.68 | ALDH1A1 (0.50) | KDM4ELMNAALDH1A1GLAGAA | |
| SCHEMBL2315975 | 0.68 | NPC1 (0.38) | KDM4ELMNAALDH1A1GAAPKM | |
| Bromide SCHEMBL2353004 | 0.67 | ALDH1A1 (0.49) | KDM4ELMNAALDH1A1GLAGAA | |
| SCHEMBL20113053 | 0.67 | PTGS2 (0.36) | PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368158-A1 | Imidazo pyridines | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1990-05-16 | — | — | EP | disclosed |
| EP-0299470-A1 | Imidazo[1,2-a]pyridines | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1989-01-18 | — | — | EP | disclosed |