Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436622 | 0.88 | PDGFRA (0.52) | NPC1RAB9AHTTSMN1; SMN2PDGFRA | |
| SCHEMBL10436621 | 0.86 | PKM (0.54) | NPC1RAB9AHTTSMN1; SMN2PDGFRA | |
| SCHEMBL10436618 | 0.85 | RECQL (0.54) | NPC1RAB9AHTTSMN1; SMN2PDGFRA | |
| SCHEMBL10436793 | 0.85 | PDGFRA (0.63) | NPC1RAB9ASMN1; SMN2PDGFRAHTR2A | |
| SCHEMBL10436626 | 0.73 | NPC1 (0.46) | NPC1RAB9AHTTHTR2CKDR | |
| SCHEMBL10436792 | 0.72 | HTR2C (0.53) | NPC1RAB9ASMN1; SMN2PDGFRAHTR2A | |
| SCHEMBL22154746 | 0.72 | HTT (0.68) | NPC1RAB9AHTTSMN1; SMN2PDGFRA | |
| SCHEMBL10436783 | 0.71 | HTR2C (0.54) | NPC1RAB9APDGFRAHTR2CKDR | |
| SCHEMBL10436769 | 0.71 | HTR2C (0.56) | NPC1RAB9AHTTSMN1; SMN2PDGFRA | |
| SCHEMBL17609477 | 0.70 | RAB9A (1.00) | NPC1RAB9AHTTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354994-A2 | Quinoline derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-02-21 | — | — | EP | disclosed |