Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436769 | 0.79 | HTR2C (0.56) | NPC1GLAMAPTHTTKDR | |
| SCHEMBL10436621 | 0.77 | PKM (0.54) | NPC1MAPTHTTKDRKMT2A | |
| SCHEMBL10436636 | 0.75 | HTR2C (0.49) | NPC1MAPTKDRKMT2AHTR2C | |
| SCHEMBL10436783 | 0.74 | HTR2C (0.54) | NPC1KDRKMT2AHTR2CHTR2B | |
| SCHEMBL10436792 | 0.73 | HTR2C (0.53) | NPC1MAPTKDRKMT2AHTR2C | |
| SCHEMBL10436623 | 0.73 | NPC1 (0.51) | NPC1MAPTHTTKDRKMT2A | |
| SCHEMBL10436622 | 0.73 | PDGFRA (0.52) | NPC1MAPTHTTKDRHTR2C | |
| SCHEMBL10436618 | 0.71 | RECQL (0.54) | NPC1HTTKDRKMT2AHTR2C | |
| SCHEMBL10436793 | 0.71 | PDGFRA (0.63) | NPC1MAPTKDRKMT2AHTR2C | |
| SCHEMBL10436634 | 0.69 | HTR2C (0.62) | MAPTKDRKMT2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354994-A2 | Quinoline derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-02-21 | — | — | EP | disclosed |