Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10353556 | 0.88 | ALDH1A1 (0.40) | ALDH1A1POLBPLAUKDM4ESMN1; SMN2 | |
| SCHEMBL7893865 | 0.86 | ALDH1A1 (0.41) | ALDH1A1POLBPLAUKDM4ESMN1; SMN2 | |
| SCHEMBL10349184 | 0.83 | ALDH1A1 (0.42) | ALDH1A1POLBPLAUKDM4ESMN1; SMN2 | |
| SCHEMBL10349447 | 0.83 | ALDH1A1 (0.42) | ALDH1A1POLBPLAUKDM4ESMN1; SMN2 | |
| SCHEMBL1747710 | 0.83 | TSHR (0.44) | ALDH1A1POLBPLAUKDM4ESMN1; SMN2 | |
| SCHEMBL29504068 | 0.83 | TSHR (0.44) | ALDH1A1POLBPLAUKDM4ESMN1; SMN2 | |
| SCHEMBL120994 | 0.81 | ALDH1A1 (0.56) | ALDH1A1POLBPLAUKDM4ESMN1; SMN2 | |
| SCHEMBL29414916 | 0.81 | ALDH1A1 (0.56) | ALDH1A1POLBPLAUKDM4ESMN1; SMN2 | |
| SCHEMBL8957637 | 0.81 | ALDH1A1 (0.41) | ALDH1A1POLBPLAUKDM4ESMN1; SMN2 | |
| SCHEMBL8773497 | 0.81 | ALDH1A1 (0.39) | ALDH1A1POLBPLAUKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397601-A1 | Benzoylphenylureas | CIBA-GEIGY AG (CH) | 1990-11-14 | — | — | EP | claimed |
| EP-0397601-A1 | Benzoylphenylureas | CIBA-GEIGY AG (CH) | 1990-11-14 | — | — | EP | disclosed |
| US-4638069-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1987-01-20 | — | — | US | disclosed |
| US-4577028-A | 5-Haloalkyl-pyridines | CIBA-GEIGY CORPORATION (US) | 1986-03-18 | — | — | US | disclosed |
| US-4550108-A | 1,3,5-Oxadiazine-2,4-diones and pesticidal use | CIBA GEIGY CORPORATION (US) | 1985-10-29 | — | — | US | disclosed |
| US-4511571-A | N-(2-Pyridyloxyphenyl)-N'-benzoyl ureas, pesticidal compositions containing same and pesticidal methods of use | CIBA GEIGY CORPORATION (US) | 1985-04-16 | — | — | US | disclosed |