Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1971207 | 0.82 | ALDH1A1 (0.58) | ALDH1A1PLAUGAAHTTRAB9A | |
| SCHEMBL10436701 | 0.81 | ALDH1A1 (0.40) | ALDH1A1PLAUGAAHTTRAB9A | |
| SCHEMBL17552426 | 0.79 | ALDH1A1 (0.42) | ALDH1A1PLAUGAAHTTRAB9A | |
| SCHEMBL8773497 | 0.78 | ALDH1A1 (0.39) | ALDH1A1PLAUGAAHTTSMN1; SMN2 | |
| SCHEMBL10353556 | 0.69 | ALDH1A1 (0.40) | ALDH1A1PLAUGAAHTTSMN1; SMN2 | |
| SCHEMBL19155254 | 0.68 | RAB9A (0.56) | ALDH1A1HTTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL31132942 | 0.67 | — | — | |
| SCHEMBL7893865 | 0.67 | ALDH1A1 (0.41) | ALDH1A1PLAUGAAHTTRAB9A | |
| SCHEMBL232870 | 0.66 | — | — | |
| SCHEMBL28605251 | 0.66 | TSHR (0.43) | ALDH1A1PLAUGAAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578595-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| US-5481013-A | INSECTICIDES, MITICIDES, CROPS | CIBA-GEIGY CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |
| US-5326901-A | 3-butenoic acid derivatives as intermediates for pesticides | CIBA-GEIGY CORPORATION (US) | 1994-07-05 | — | — | US | disclosed |