Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313204 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL10436701 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL8957637 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL10353556 | 0.69 | ALDH1A1 (0.40) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL19155254 | 0.68 | RAB9A (0.56) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL7893865 | 0.67 | ALDH1A1 (0.41) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL31253346 | 0.66 | — | — | |
| SCHEMBL5261076 | 0.66 | — | — | |
| SCHEMBL28605251 | 0.66 | TSHR (0.43) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL10349184 | 0.64 | ALDH1A1 (0.42) | ALDH1A1HTTLMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577555-B1 | Derivatives of carboxylic acids | CIBA GEIGY AG (CH) | 1997-11-05 | — | — | EP | disclosed |
| US-5578595-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| US-5481013-A | INSECTICIDES, MITICIDES, CROPS | CIBA-GEIGY CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |
| US-5326901-A | 3-butenoic acid derivatives as intermediates for pesticides | CIBA-GEIGY CORPORATION (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0577555-A1 | Derivatives of carboxylic acids | CIBA-GEIGY AG (CH) | 1994-01-05 | — | — | EP | disclosed |