SCHEMBL10436723

SCHEMBL10436723

Cc1cc(C)c(C(C)c2cc(C)c(C)cc2C)cc1C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4972071 0.81 LMNA (0.39) CYP3A4TSHRMAPK1LMNA
SCHEMBL30485784 0.78 CYP2D6 (0.50) CYP3A4TSHRMAPK1LMNA
SCHEMBL1176482 0.78 CYP2D6 (0.50) CYP3A4TSHRMAPK1LMNA
SCHEMBL26939188 0.77 CYP3A4 (0.33) CYP3A4TSHRMAPK1
SCHEMBL16962087 0.77 CYP3A4 (0.33) CYP3A4TSHRMAPK1
SCHEMBL12471360 0.77 CYP3A4 (0.39) CYP3A4TSHRMAPK1
SCHEMBL14036694 0.77 CYP3A4 (0.39) CYP3A4TSHRMAPK1LMNA
SCHEMBL16900309 0.75 POLB (0.46) LMNA
SCHEMBL8501588 0.75 LMNA (0.50) CYP3A4MAPK1LMNA
SCHEMBL8674666 0.73 LMNA (0.42) CYP3A4TSHRMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110225957-A With chiral optically active new material 香港科技大学 2019-09-10 CN disclosed
EP-0367228-A2 Heat-sensitive recording material ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1990-05-09 EP disclosed