Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | SELL | P14151 | 4/20 | 0.36 |
| ▸ | SELP | P16109 | 4/20 | 0.36 |
| ▸ | SELE | P16581 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1258491 | 0.82 | GABRA1 (0.52) | PTPN5AKR1B1GABRA1GABRB2PDCD1 | |
| SCHEMBL10437300 | 0.81 | HTR7 (0.39) | HTR7MAPK1PTGER1PTGER4PTGER3 | |
| SCHEMBL11061615 | 0.76 | GABRA1 (0.52) | PTPN5AKR1B1GABRA1GABRB2 | |
| SCHEMBL5932002 | 0.75 | AGXT (0.47) | AOC3 | |
| SCHEMBL20684744 | 0.75 | APP (0.41) | AKR1B1GABRA1GABRB2MMP3 | |
| SCHEMBL8389267 | 0.75 | IAPP (0.52) | AKR1B1GABRA1GABRB2MAPK1 | |
| SCHEMBL20262937 | 0.74 | SLC7A5 (0.39) | — | |
| SCHEMBL16273850 | 0.71 | ENPP2 (0.52) | GABRA1GABRB2MAPK1 | |
| SCHEMBL20906311 | 0.70 | GABRA1 (0.45) | GABRA1GABRB2PDCD1CD274 | |
| SCHEMBL5785094 | 0.70 | ALDH1A1 (0.50) | GABRA1GABRB2PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385937-A1 | Curable blends based on aromatic bismaleinimides | CIBA-GEIGY AG (CH) | 1990-09-05 | — | — | EP | disclosed |
| EP-0235084-A2 | Hot-curable compositions containing substituted bicyclo[2,2,1]hept-5-ene-2,3 imides of dicarboxylic acids and polymalein imide | CIBA-GEIGY AG (CH) | 1987-09-02 | — | — | EP | disclosed |