Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16738992 | 0.73 | MGMT (0.50) | MGMTCYP19A1CYP11B1CYP11B2LMNA | |
| SCHEMBL6178097 | 0.72 | PIN1 (0.49) | MGMTCYP19A1NPC1CYP1A2RAB9A | |
| SCHEMBL7691338 | 0.71 | GSTP1 (0.54) | NPSR1SMN1; SMN2RAB9AMAPTGSTP1 | |
| SCHEMBL6284658 | 0.71 | HTR1A (0.50) | MGMTSMN1; SMN2NPC1RAB9APIN1 | |
| SCHEMBL8316680 | 0.70 | MAOB (0.55) | LMNASMN1; SMN2CYP1A2RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL3092379 | 0.70 | HTR1A (0.49) | MGMTSMN1; SMN2NPC1RAB9APIN1 | |
| SCHEMBL28160763 | 0.70 | CYP19A1 (0.48) | CYP19A1CYP11B1CYP11B2LMNASMN1; SMN2 | |
| SCHEMBL25355454 | 0.69 | MGMT (0.46) | MGMTCYP19A1CYP11B1CYP11B2LMNA | |
| SCHEMBL31190976 | 0.69 | MAOB (0.47) | MGMTCYP19A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL26022683 | 0.69 | MAOB (0.47) | MGMTCYP19A1LMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360566-A2 | Lipoxygenase/cyclooxygenase inhibiting benzoxazolones | PFIZER INC. (US) | 1990-03-28 | — | — | EP | disclosed |