Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19302712 | 0.75 | EPHX1 (0.34) | CA1CA2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL12148586 | 0.70 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1 | |
| SCHEMBL2624975 | 0.70 | ALDH1A1 (0.38) | ALDH1A1MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9913255 | 0.70 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1 | |
| SCHEMBL12417902 | 0.69 | CA1 (0.45) | CA1CA2ALDH1A1L3MBTL1F2 | |
| SCHEMBL27849194 | 0.67 | ALDH1A1 (0.39) | CA1CA2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL4461436 | 0.67 | — | — | |
| SCHEMBL11917859 | 0.67 | ALDH1A1 (0.35) | CA1CA2ALDH1A1L3MBTL1F2 | |
| SCHEMBL4948382 | 0.66 | — | — | |
| SCHEMBL8912403 | 0.64 | CA2 (0.50) | CA1CA2MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399291-A2 | Substituted (Quinoline-2-yl-methoxy)phenyl-acyl-sulphonamides and cyanamides , process for their preparation and their use in medicines | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |