SCHEMBL2624975

SCHEMBL2624975

CC(=O)C(F)(F)S(C)(=O)=O

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9913255 0.77 ALDH1A1 (0.57) ALDH1A1L3MBTL1
SCHEMBL28980551 0.77 ALDH1A1 (0.57) ALDH1A1L3MBTL1
SCHEMBL12148586 0.77 ALDH1A1 (0.38) ALDH1A1L3MBTL1
SCHEMBL15491315 0.76 DGAT1 (0.34) ALDH1A1L3MBTL1MAPK1SMN1; SMN2
SCHEMBL12417902 0.74 CA1 (0.45) ALDH1A1L3MBTL1
SCHEMBL27849194 0.73 ALDH1A1 (0.39) ALDH1A1L3MBTL1MAPK1SMN1; SMN2
SCHEMBL11917859 0.72 ALDH1A1 (0.35) ALDH1A1L3MBTL1
SCHEMBL10438403 0.70 CA1 (0.35) ALDH1A1L3MBTL1MAPK1SMN1; SMN2
SCHEMBL22289461 0.70 CA2 (0.33) ALDH1A1L3MBTL1
SCHEMBL13070971 0.69 ALDH1A1 (0.36) ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9951164-B2 Non-ionic aryl ketone based polymeric photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 US disclosed
US-20180044459-A1 NON-IONIC ARYL KETONE BASED POLYMERIC PHOTO-ACID GENERATORS CENTRAL GLASS CO., LTD. (JP) 2018-02-15 US disclosed
US-8557499-B2 Actinic-ray- or radiation-sensitive resin composition, compound and method of forming pattern using the composition FUJIFILM CORPORATION (JP) 2013-10-15 US disclosed
US-8283102-B2 Photoacid generator, copolymer, chemically amplified resist composition, and method of forming pattern using the chemically amplified resist composition KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2012-10-09 US disclosed
US-8158327-B2 Onium salt compound, polymer compound comprising the salt compound, chemically amplified resist composition comprising the polymer compound, and method for patterning using the composition KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2012-04-17 US disclosed
US-20120076996-A1 RESIST COMPOSITION, RESIST FILM THEREFROM AND METHOD OF FORMING PATTERN THEREWITH FUJIFILM CORPORATION (JP) 2012-03-29 US disclosed
US-8026390-B2 Photoacid generator containing aromatic ring Korea Kumho Petrochenicals Co., Ltd. (KR) 2011-09-27 US disclosed
US-20110008731-A1 ACTINIC-RAY-OR RADIATION-SENSITIVE RESIN COMPOSITION, COMPOUND AND METHOD OF FORMING PATTERN USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-13 US disclosed
US-20100143843-A1 PHOTOACID GENERATOR, COPOLYMER, CHEMICALLY AMPLIFIED RESIST COMPOSITION, AND METHOD OF FORMING PATTERN USING THE CHEMICALLY AMPLIFIED RESIST COMPOSITION KOREA KUMHO PETROCHEMICAL CO., LTD. 2010-06-10 US disclosed
US-20100113818-A1 Photoacid generator containing aromatic ring KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2010-05-06 US disclosed
US-20100075256-A1 Onium salt compound, polymer compound comprising the salt compound, chemically amplified resist composition comprising the polymer compound, and method for patterning using the composition KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2010-03-25 US disclosed
EP-0996606-B1 CATALYSED FLUORINATION OF CARBONYL COMPOUNDS F2 CHEMICALS LTD (GB) 2002-01-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044459-A1 NON-IONIC ARYL KETONE BASED POLYMERIC PHOTO-ACID GENERATORS PPARG, PPARA, PPARD ALDH1A1 568/4885L3MBTL1 1806/4885MAPK1 777/4885
US-20110008731-A1 ACTINIC-RAY-OR RADIATION-SENSITIVE RESIN COMPOSITION, COMPOUND AND METHOD OF FORMING PATTERN USING THE COMPOSITION RER1, XRN2, RXRA ALDH1A1 2195/4885L3MBTL1 4102/4885MAPK1 2514/4885
US-20100113818-A1 Photoacid generator containing aromatic ring HAO2, PAH, PPOX ALDH1A1 1112/4885L3MBTL1 3860/4885MAPK1 2032/4885
US-20100143843-A1 PHOTOACID GENERATOR, COPOLYMER, CHEMICALLY AMPLIFIED RESIST COMPOSITION, AND METHOD OF FORMING PATTERN USING THE CHEMICALLY AMPLIFIED RESIST COMPOSITION POLL, PARG, POLH ALDH1A1 4004/4885L3MBTL1 4613/4885MAPK1 2957/4885
US-20100075256-A1 Onium salt compound, polymer compound comprising the salt compound, chemically amplified resist composition comprising the polymer compound, and method for patterning using the composition ARF5, ARL1, FGFR2 ALDH1A1 3581/4885L3MBTL1 3398/4885MAPK1 612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.