Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 2/20 | 0.47 |
| ▸ | CDK8 | P49336 | 2/20 | 0.47 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | MYLK | Q15746 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CILK1 | Q9UPZ9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10439316 | 0.85 | ALDH1A1 (0.48) | HTTGAACCNCCDK8ALDH1A1 | |
| SCHEMBL563558 | 0.84 | GAA (0.52) | SMN1; SMN2L3MBTL1GAAALDH1A1 | |
| SCHEMBL31147874 | 0.80 | GRIN2B (0.43) | TSHRGAAALDH1A1 | |
| SCHEMBL29078195 | 0.80 | KDM4E (0.51) | SMN1; SMN2TSHRHTTMEN1KMT2A | |
| SCHEMBL25433566 | 0.80 | L3MBTL1 (0.59) | L3MBTL1CCNCCDK8KCNJ6KCNJ5 | |
| SCHEMBL29427375 | 0.79 | L3MBTL1 (0.43) | SMN1; SMN2L3MBTL1CCNCCDK8KCNJ6 | |
| SCHEMBL12124191 | 0.79 | ALPI (0.49) | SMN1; SMN2HTTCYP2C19ALDH1A1 | |
| SCHEMBL28397299 | 0.76 | SRC (0.59) | SMN1; SMN2TSHRHTTMEN1KMT2A | |
| SCHEMBL12968057 | 0.76 | GSK3A (0.44) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL14125781 | 0.76 | GSK3A (0.44) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388659-A1 | Azole-1-alkanamides as antiarrhythmic agents and preparation thereof | STERLING DRUG INC. (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4888352-A | 3,4, or 5-aryl-1H-pyrazole-1-alkanamides as antiarrhythmic agents, compositions and use | STERLING DRUG INC. (US) | 1989-12-19 | — | — | US | disclosed |