Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31147921 | 0.81 | PDK2 (0.45) | GRIN2BKCNH2NAMPTS1PR1 | |
| SCHEMBL10439151 | 0.80 | SMN1; SMN2 (0.55) | ALDH1A1TSHRGAA | |
| SCHEMBL22642936 | 0.80 | KCNH2 (0.53) | GRIN2BKCNH2NAMPT | |
| SCHEMBL10439316 | 0.80 | ALDH1A1 (0.48) | ALDH1A1GAA | |
| SCHEMBL19155220 | 0.79 | CTSK (0.53) | GRIN2BKCNH2NAMPT | |
| SCHEMBL23162255 | 0.75 | PIK3C3 (0.40) | SCD | |
| SCHEMBL22775550 | 0.75 | GRIN2B (0.57) | GRIN2B | |
| SCHEMBL31147878 | 0.73 | GRIN2B (0.46) | GRIN2BALDH1A1TSHRMAPK1GAA | |
| SCHEMBL12124191 | 0.73 | ALPI (0.49) | ALDH1A1MAPK1 | |
| SCHEMBL16648923 | 0.73 | HCRTR1 (0.45) | GRIN2BKCNH2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695240-A2 | CYCLIC VINYL SULFONE WRN INHIBITORS | Nimbus Wadjet, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024215923-A2 | CYCLIC VINYL SULFONE WRN INHIBITORS | NIMBUS WADJET, INC. (US) | 2024-10-17 | — | — | WO | disclosed |