Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325362 | 0.88 | BLM (0.37) | LMNA | |
| SCHEMBL9325196 | 0.88 | CYP3A4 (0.33) | — | |
| SCHEMBL7293488 | 0.82 | CA2 (0.39) | LMNA | |
| SCHEMBL9326312 | 0.74 | — | — | |
| SCHEMBL15501726 | 0.73 | LMNA (0.43) | LMNA | |
| SCHEMBL9837929 | 0.72 | — | — | |
| SCHEMBL9482274 | 0.72 | — | — | |
| SCHEMBL9680134 | 0.70 | BLM (0.40) | LMNA | |
| SCHEMBL9326168 | 0.70 | CYP3A4 (0.35) | — | |
| SCHEMBL9670027 | 0.70 | ADRB2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369812-A2 | Anti-inflammatory 5-hydroxy-2-furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |