Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8951293 | 0.90 | ALDH1A1 (0.51) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL2402155 | 0.90 | ALDH1A1 (0.51) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL30583203 | 0.85 | MME (0.40) | ALDH1A1MMEMAPT | |
| SCHEMBL29962128 | 0.85 | MME (0.40) | ALDH1A1MMEMAPT | |
| SCHEMBL8869145 | 0.82 | CASP1 (0.43) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL991835 | 0.82 | CASP1 (0.43) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10882651 | 0.82 | CASP1 (0.43) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10608088 | 0.81 | CASP1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL7269277 | 0.78 | TAS1R3 (0.51) | ALDH1A1FOLH1 | |
| SCHEMBL7269272 | 0.78 | TAS1R3 (0.51) | ALDH1A1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372582-A2 | 6-Aminoalkyl carbapenems | Bristol-Myers Squibb Company (US) | 1990-06-13 | — | — | EP | disclosed |