Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 8/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384103 | 0.87 | PPOX (0.41) | PPOXARKMT2AMEN1KDM4E | |
| SCHEMBL10440441 | 0.83 | PPOX (0.41) | PPOXARSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10440318 | 0.77 | AR (0.45) | PPOXARSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL9664148 | 0.76 | PPOX (0.45) | PPOXARSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL10938117 | 0.75 | PPOX (0.51) | PPOXARSMN1; SMN2 | |
| SCHEMBL10940936 | 0.75 | PPOX (0.47) | PPOXARSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL10613566 | 0.75 | PPOX (0.65) | PPOXARSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL10463025 | 0.74 | AR (0.40) | ARSMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL10510772 | 0.74 | PPOX (0.53) | PPOX | |
| SCHEMBL9273018 | 0.74 | LMNA (0.35) | PPOXARKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363585-A1 | N-aryl nitrogen heterocycles | BAYER AG (DE) | 1990-04-18 | — | — | EP | disclosed |