SCHEMBL10440743

SCHEMBL10440743

CCOC(=O)C(CCC(=O)O)C(=O)c1c(Cl)nc(Cl)c(F)c1CC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9088405 0.88 TDP1 (0.31) ALDH1A1
SCHEMBL10440742 0.78 ALDH1A1 (0.31) ALDH1A1L3MBTL1
SCHEMBL6170105 0.75 KEAP1 (0.47)
SCHEMBL2096530 0.75 ALDH1A1 (0.41) ALDH1A1
Hydrochloric Acid SCHEMBL10440713 0.74 ALDH1A1 (0.40) ALDH1A1
SCHEMBL2092313 0.71 GAA (0.38) ALDH1A1L3MBTL1
SCHEMBL2818593 0.68 GABRP (0.48) ALDH1A1L3MBTL1
SCHEMBL7373212 0.67 KMT2A (0.43) ALDH1A1
SCHEMBL10441066 0.66 NPSR1 (0.34)
SCHEMBL10440745 0.65 CYP1A2 (0.30) ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0387802-A2 5-Substituted-1,4-dihydro-4-oxonaphthyridine-3-carboxylate antibacterial agents Bristol-Myers Squibb Company (US) 1990-09-19 EP disclosed