Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.48 |
| ▸ | GABRD | O14764 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRE | P78334 | 2/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259052 | 0.90 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6885934 | 0.87 | TDP1 (0.53) | TDP1MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL11042683 | 0.84 | FFAR4 (0.52) | TDP1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL27514817 | 0.84 | FFAR4 (0.52) | TDP1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4613905 | 0.83 | TDP1 (0.50) | TDP1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL11596985 | 0.82 | PPARG (0.48) | TDP1MEN1KMT2ACYP1A2POLB | |
| SCHEMBL11596983 | 0.82 | PPARG (0.48) | TDP1MEN1KMT2ACYP1A2POLB | |
| SCHEMBL6650291 | 0.82 | L3MBTL1 (0.56) | TDP1MEN1KMT2ACYP1A2POLB | |
| SCHEMBL10843170 | 0.82 | ALDH1A1 (0.44) | TDP1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL28899057 | 0.81 | TDP1 (0.47) | TDP1MEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110318290-A1 | Compounds and Methods for Inhibiting Axillary Malodour | GIVAUDAN SA (CH) | 2011-12-29 | — | — | US | disclosed |
| EP-2041145-B1 | AZATRICYCLIC COMPOUNDS AND THEIR USE | GLAXO GROUP LTD (GB) | 2010-10-27 | — | — | EP | disclosed |
| US-7264956-B2 | N-alpha-acyl-glutamine-aminoacylase for identifying enzyme inhibitors which prevent/supress sweating odor; deodorants | GIVAUDAN SA (CH) | 2007-09-04 | — | — | US | disclosed |
| EP-1811034-A2 | Compounds and method for inhibiting axillary malodour | Givaudan SA (CH) | 2007-07-25 | — | — | EP | disclosed |
| US-20040241795-A1 | Compounds and methods for inhibiting axillary malodour | GIVAUDAN SA (CH) | 2004-12-02 | — | — | US | disclosed |
| EP-1387891-A2 | COMPOUNDS AND METHODS FOR INHIBITING AXILLARY MALODOUR | Givaudan SA (CH) | 2004-02-11 | — | — | EP | disclosed |
| EP-1305407-A2 | PREPARATION OF DICARBOXYLIC ACID MONOESTERS FROM CYANOCARBOXYLIC ACID ESTERS | E. I. du Pont de Nemours and Company (US) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002092024-A2 | COMPOUNDS AND METHODS FOR INHIBITING AXILLARY MALODOUR | GIVAUDAN SA (CH) | 2002-11-21 | — | — | WO | disclosed |
| US-6455730-B1 | CONTACTING CYANOPROPANOIC ACID METHYL ESTER WITH NITRILASE ISOLATED FROM ACIDOVORAX TO FORM BUTANEDIOIC ACID MONOMETHYL ESTER WITH NO PRODUCTION OF CYANOPROPIONIC ACID OR BUTANEDIOIC ACID | E. I. DU PONT DE NEMOURS & COMPANY | 2002-09-24 | — | — | US | disclosed |
| WO-2002012527-A2 | PREPARATION OF DICARBOXYLIC ACID MONOESTERS FROM CYANOCARBOXYLIC ACID ESTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-02-14 | — | — | WO | disclosed |
| CN-1049215-C | Process for preparing benzoquinazoline thymidylate synthase inhibitors | WELLOCOME FOUNDATION LTD (GB) | 2000-02-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110318290-A1 | Compounds and Methods for Inhibiting Axillary Malodour | TYR, AOX1, APEH | GABRP 4005/4885GABRD 2726/4885GABRA1 4086/4885 |
| US-20040241795-A1 | Compounds and methods for inhibiting axillary malodour | AOX1, TYR, ME1 | GABRP 3904/4885GABRD 3330/4885GABRA1 4024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.