Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ERN1 | O75460 | 4/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783697 | 0.85 | NPC1 (0.36) | TDP1ALDH1A1PDGFRBPDGFRAMET | |
| SCHEMBL10780332 | 0.82 | PDGFRB (0.34) | ALDH1A1PDGFRBPDGFRAMETSMN1; SMN2 | |
| SCHEMBL10757304 | 0.78 | KMT2A (0.38) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL10782720 | 0.76 | MAPT (0.44) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL16963494 | 0.75 | ALDH1A1 (0.42) | TDP1CYP1A2ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL3412523 | 0.74 | CASP6 (0.57) | TDP1CYP1A2CYP2C19ALDH1A1PDGFRB | |
| SCHEMBL31637162 | 0.73 | S1PR4 (0.32) | TDP1PDGFRBPDGFRAMET | |
| SCHEMBL11093576 | 0.71 | IDH1 (0.34) | PDGFRBPDGFRAPDE3BPDE3A | |
| SCHEMBL25249080 | 0.71 | TDP1 (0.48) | TDP1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10783720 | 0.71 | P2RY12 (0.43) | CYP3A4ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106949-B1 | 3,7-DICHLORO-8-QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE TO COMBAT UNDESIRED PLANT GROWTH | BASF Aktiengesellschaft (DE) | 1987-04-15 | — | — | EP | claimed |
| EP-0106949-A2 | 3,7-Dichloro-8-quinoline derivatives, process for their preparation and their use to combat undesired plant growth | BASF Aktiengesellschaft (DE) | 1984-05-02 | — | — | EP | claimed |
| EP-0399394-A1 | 8-Azolylmethylquinolines | BASF Aktiengesellschaft (DE) | 1990-11-28 | — | — | EP | disclosed |
| EP-0106949-B1 | 3,7-DICHLORO-8-QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE TO COMBAT UNDESIRED PLANT GROWTH | BASF Aktiengesellschaft (DE) | 1987-04-15 | — | — | EP | disclosed |
| EP-0168634-A1 | Herbicidal agents based on dichloroquinoline derivatives | BASF Aktiengesellschaft (DE) | 1986-01-22 | — | — | EP | disclosed |
| EP-0106949-A2 | 3,7-Dichloro-8-quinoline derivatives, process for their preparation and their use to combat undesired plant growth | BASF Aktiengesellschaft (DE) | 1984-05-02 | — | — | EP | disclosed |
| EP-0060429-B1 | DICHLOROQUINOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1984-01-25 | — | — | EP | disclosed |
| EP-0060429-A1 | Dichloroquinoline derivatives, their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1982-09-22 | — | — | EP | disclosed |