Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783697 | 0.81 | NPC1 (0.36) | KMT2AKDM4EHPGDTSHRMAPT | |
| SCHEMBL10440960 | 0.78 | TDP1 (0.46) | KMT2AKDM4ETSHRMAPTCYP2D6 | |
| SCHEMBL10780332 | 0.78 | PDGFRB (0.34) | TSHRPDGFRBPDGFRAALDH1A1CYP2C9 | |
| SCHEMBL16963527 | 0.77 | ALDH1A1 (0.46) | KMT2AKDM4EL3MBTL1HPGDTSHR | |
| SCHEMBL16963525 | 0.77 | ALDH1A1 (0.46) | KMT2AKDM4EL3MBTL1HPGDTSHR | |
| SCHEMBL10782720 | 0.72 | MAPT (0.44) | KMT2AKDM4EL3MBTL1HPGDMAPT | |
| SCHEMBL20073537 | 0.70 | HPGD (0.38) | KMT2AKDM4EL3MBTL1HPGDTSHR | |
| SCHEMBL29055093 | 0.69 | HTR5A (0.39) | KMT2AKDM4EHPGDTSHRMAPT | |
| SCHEMBL10957077 | 0.68 | HPGD (0.37) | KMT2AKDM4EL3MBTL1HPGDTSHR | |
| SCHEMBL6069694 | 0.68 | PLAU (0.43) | KMT2AKDM4EL3MBTL1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106949-B1 | 3,7-DICHLORO-8-QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE TO COMBAT UNDESIRED PLANT GROWTH | BASF Aktiengesellschaft (DE) | 1987-04-15 | — | — | EP | claimed |
| EP-0106949-A2 | 3,7-Dichloro-8-quinoline derivatives, process for their preparation and their use to combat undesired plant growth | BASF Aktiengesellschaft (DE) | 1984-05-02 | — | — | EP | claimed |
| EP-0224823-A2 | Quinoline derivatives and their use in combating unwanted plant growth | BASF Aktiengesellschaft (DE) | 1987-06-10 | — | — | EP | disclosed |
| EP-0106949-B1 | 3,7-DICHLORO-8-QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE TO COMBAT UNDESIRED PLANT GROWTH | BASF Aktiengesellschaft (DE) | 1987-04-15 | — | — | EP | disclosed |
| EP-0106949-A2 | 3,7-Dichloro-8-quinoline derivatives, process for their preparation and their use to combat undesired plant growth | BASF Aktiengesellschaft (DE) | 1984-05-02 | — | — | EP | disclosed |