Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783697 | 0.85 | NPC1 (0.36) | PDGFRBPDGFRAALDH1A1METLMNA | |
| SCHEMBL10440960 | 0.82 | TDP1 (0.46) | PDGFRBPDGFRAALDH1A1METLMNA | |
| SCHEMBL10757304 | 0.78 | KMT2A (0.38) | PDGFRBPDGFRAALDH1A1LMNACYP2C9 | |
| SCHEMBL10782720 | 0.76 | MAPT (0.44) | ALDH1A1LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL28235117 | 0.73 | PDGFRB (0.34) | PDGFRBPDGFRA | |
| SCHEMBL31637314 | 0.73 | S1PR4 (0.32) | PDGFRBPDGFRA | |
| SCHEMBL18987770 | 0.71 | MGAM (0.46) | PDGFRBPDGFRATSHR | |
| SCHEMBL25290715 | 0.71 | ALDH1A1 (0.37) | ALDH1A1CYP2C9 | |
| SCHEMBL31465323 | 0.71 | ALDH1A1 (0.37) | ALDH1A1CYP2C9 | |
| SCHEMBL11094186 | 0.70 | KDM4E (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106949-B1 | 3,7-DICHLORO-8-QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE TO COMBAT UNDESIRED PLANT GROWTH | BASF Aktiengesellschaft (DE) | 1987-04-15 | — | — | EP | disclosed |
| EP-0106949-A2 | 3,7-Dichloro-8-quinoline derivatives, process for their preparation and their use to combat undesired plant growth | BASF Aktiengesellschaft (DE) | 1984-05-02 | — | — | EP | disclosed |