Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251813 | 0.80 | FFAR4 (0.39) | FFAR4CYP11B1CYP11B2BCL2L1BAD | |
| SCHEMBL20573246 | 0.78 | FABP7 (0.42) | FFAR4CYP11B1CYP11B2ALDH1A1LMNA | |
| SCHEMBL7053967 | 0.78 | FABP7 (0.42) | FFAR4CYP11B1CYP11B2KDM4EALDH1A1 | |
| SCHEMBL7550089 | 0.76 | HSD17B10 (0.55) | HSD17B10APPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6205516 | 0.76 | TTR (0.53) | KDM4EMEN1USP2ALDH1A1DHFR | |
| SCHEMBL10600475 | 0.74 | TTR (0.62) | KDM4EMEN1USP2ALDH1A1DHFR | |
| SCHEMBL29788333 | 0.73 | CCNT1 (0.55) | FFAR4BCL2L1BADCA1CA2 | |
| SCHEMBL2039640 | 0.73 | CCNT1 (0.55) | FFAR4BCL2L1BADCA1CA2 | |
| SCHEMBL14829704 | 0.73 | CES2 (0.47) | KDM4EMEN1LMNAHPGDKMT2A | |
| SCHEMBL8760698 | 0.73 | HTT (0.39) | ALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396014-A2 | Substituted biphenylcarboxylic acids, process for their preparation and new intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-07 | — | — | EP | disclosed |